CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)

Author:

Kelly Louise M,Yu Jin-Chen,Boulton Christina L,Apatira Mutiah,Li Jason,Sullivan Carol M,Williams Ifor,Amaral Sonia M,Curley David P,Duclos Nicole,Neuberg Donna,Scarborough Robert M,Pandey Anjali,Hollenbach Stanley,Abe Keith,Lokker Nathalie A,Gilliland D.Gary,Giese Neill A

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference52 articles.

1. FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group;Abu-Duhier;Br. J. Haematol.,2000

2. Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia;Abu-Duhier;Br. J. Haematol.,2001

3. Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival;Benekli;Blood,2002

4. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148);Beran;Clin. Cancer Res.,1998

5. Regulation of constitutive STAT5 phosphorylation in acute myeloid leukemia blasts;Birkenkamp;Leukemia,2001

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