Generating improved single-chain Fv molecules for tumor targeting

Author:

Adams Gregory P,Schier Robert

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference63 articles.

1. Improving the tumor specificity and retention of antibody-based molecules;Adams;In Vivo,1998

2. Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv;Adams;Cancer Res.,1993

3. Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies;Adams;Cancer Res.,1998

4. What are the determinants of antibody-based targeting?;Adams;Proc. Am. Assoc. Cancer Res.,1998

5. Prolonged in vivo tumor retention of a human diabody targeting the extracellular domain of human HER2/neu;Adams;Brit. J. Cancer,1998

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