Toward the effective synthesis of bivalent Folate-targeted PEGylated cancer diagnostic and therapeutic agents using chemo-enzymatic processes

Author:

Puskas Judit E.,Molnar Kristof,Krisch Eniko

Funder

Ohio State University

Breast Cancer Innovation Foundation

Publisher

Elsevier BV

Subject

Materials Chemistry,Physical and Theoretical Chemistry,Spectroscopy,Condensed Matter Physics,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials

Reference51 articles.

1. Cancer deaths have fallen drastically over the last 25 years;Ducharme,2019

2. Advances in targeting the folate receptor in the treatment/imaging of cancers;Fernández;Chem. Sci.,2018

3. Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis;Leamon;Proc. Natl. Acad. Sci.,1991

4. Clinical trials, A Service of the U.S. National Institutes of Health, (n.d.). https://clinicaltrials.gov/ct2/results?cond=&term=EC17&cntry=&state=&city=&dist= (accessed May 1, 2019).

5. Folate receptors and transporters: biological role and diagnostic/therapeutic targets in cancer and other diseases;Frigerio;J. Exp. Clin. Cancer Res.,2019

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