Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells-Reference-Cited by-同舟云学术

Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells

Published:2008-05 Issue:1 Volume:76 Page:15-22
ISSN:0026-2862
Container-title:Microvascular Research
language:en
Short-container-title:Microvascular Research

Author:

Amin Dhara N.,Bielenberg Diane R.,Lifshits Eugene,Heymach John V.,Klagsbrun Michael

Publisher

Elsevier BV

Subject

Cell Biology,Cardiology and Cardiovascular Medicine,Biochemistry

Reference43 articles.

1. Neuregulin-regulated gene expression in mammary carcinoma cells;Amin;Exp. Cell Res.,2005

2. Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors;Amin;Cancer Res.,2006

3. HER3 and mutant EGFR meet MET;Arteaga;Nat. Med.,2007

4. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors;Baker;Neoplasia,2006

5. Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma;Bruns;Cancer Res.,2000

Cited by 49 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting EGFR and VEGFR-2 Kinases With Nanoparticles: A Computational Approach for Cancer Therapy Advancement;Cancer Investigation;2024-02-07

2. ‘ In silico ’ repurposing new inhibitors of EGFR and VEGFR-2 kinases via biophysical mechanisms;Journal of Biomolecular Structure and Dynamics;2023-09-27

3. Design, synthesis, in vitro and in silico evaluation of anti-colorectal cancer activity of curcumin analogues containing 1,3-diphenyl-1H-pyrazole targeting EGFR tyrosine kinase;Biochimica et Biophysica Acta (BBA) - General Subjects;2023-09

4. Novel 4-thiophenyl-pyrazole, pyridine, and pyrimidine derivatives as potential antitumor candidates targeting both EGFR and VEGFR-2; design, synthesis, biological evaluations, andin silicostudies;RSC Advances;2023

5. The Neurokinin-1 Receptor: A Promising Antitumor Target;Receptors;2022-11-07