Homology modeling and structural analysis of 11β-hydroxysteroid dehydrogenase type 2-Reference-Cited by-同舟云学术

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Homology modeling and structural analysis of 11β-hydroxysteroid dehydrogenase type 2

Published:2011-04 Issue:4 Volume:46 Page:1325-1330
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Yamaguchi Hideaki,Akitaya Tatsuo,Yu Tao,Kidachi Yumi,Kamiie Katsuyoshi,Noshita Toshiro,Umetsu Hironori,Ryoyama Kazuo

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference42 articles.

1. Short-chain dehydrogenase/reductase (SDR) relationships: a large family with eight clusters common to human, animal, and plant genomes;Kallberg;Protein Sci.,2002

2. Short-chain dehydrogenases/reductases (SDR);Jornvall;Biochemistry,1995

3. Tyr-179 and Lys-183 are essential for enzymatic activity of 11 beta-hydroxysteroid dehydrogenase;Obeid;Biochem. Biophys. Res. Commun.,1992

4. Active site directed mutagenesis of 3 beta/17 beta-hydroxysteroid dehydrogenase establishes differential effects on short-chain dehydrogenase/reductase reactions;Oppermann;Biochemistry,1997

5. Critical residues for structure and catalysis in shortchain dehydrogenases/reductases;Filling;J. Biol. Chem.,2002

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of 11β-HSD1 inhibitors through enhanced sampling methods;Chemical Communications;2022

2. Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole;Toxicology and Applied Pharmacology;2021-02

3. Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals;The Journal of Steroid Biochemistry and Molecular Biology;2020-05

4. 11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ;Journal of Lipid Research;2019-09

5. Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2;The Journal of Steroid Biochemistry and Molecular Biology;2019-06

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