Synthesis of 7,9-diazabicyclo[4.2.2]decanes as conformationally restricted κ receptor agonists: Fine tuning of the dihedral angle of the ethylenediamine pharmacophore-Reference-Cited by-同舟云学术

Synthesis of 7,9-diazabicyclo[4.2.2]decanes as conformationally restricted κ receptor agonists: Fine tuning of the dihedral angle of the ethylenediamine pharmacophore

Published:2011-06 Issue:6 Volume:46 Page:1972-1982
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Sunnam Sunil K.,Rack Elisabeth,Schepmann Dirk,Wünsch Bernhard

Funder

Government of the state Northrhine-Westfalia

DAAD

DFG

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference29 articles.

1. Kappa-opioid receptor-mediated antinociception in the rat. 1. Comparative actions of mu-opioids and kappa-opioids against noxious thermal, pressure and electrical stimuli;Millan;J. Pharmacol. Exp. Ther.,1989

2. Recent developments in non-peptide kappa receptors;Scopes;Drugs Fut.,1993

3. Opioid-Agonisten und –Antagonisten, Opioid-Rezeptoren;Holzgrabe;Pharmazie,1997

4. Delta and kappa opioid receptors as suitable drug targets for pain;Vanderath;Clin. J. Pain,2010

5. Effects of κ-opioid receptor agonists on long-term cocaine use and dopamine neurotransmission;Collins;Eur. J. Pharmacol.,2001

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