Synthesis and biological evaluation of aurora kinases inhibitors based on N -trisubstituted pyrimidine scaffold-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of aurora kinases inhibitors based on N -trisubstituted pyrimidine scaffold

Published:2018-02 Issue: Volume:145 Page:805-812
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Long Liang,Luo Yu,Hou Zhi-Jie,Ma Hua-Juan,Long Zi-Jie,Tu Zheng-Chao,Huang Lin-Jie,Liu Quentin,Lu Gui^ORCID

Funder

Guangdong Innovative Research Team Program

National High-tech R&D Program of China

National Natural Science Foundation of China

Guangdong Province Natural Science Foundation

Science and Technology Program of Guangzhou

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference23 articles.

1. Discovery and development of aurora kinase inhibitors as anticancer agents;Pollard;J. Med. Chem.,2009

2. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles;Glover;Cell,1995

3. Targeted anti-mitotic therapies: can we improve on tubulin agents?;Jackson;Nat. Rev. Canc.,2007

4. Roles of aurora kinases in mitosis and tumorigenesis;Fu;Mol. Canc. Therapeut.,2007

5. A class of 2,4-bisanilinopyrimidine aurora A inhibitors with unusually high selectivity against aurora;Aliagas-Martin;B. J. Med. Chem.,2009

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2. Synthesis of pyrimidine ligand and its mononuclear metal(II)/(III) complexes: Spectroscopic characterization, thermal, DFT, molecular docking, antimicrobial and anticancer studies;Inorganic Chemistry Communications;2023-09

3. Discovery of a first-in-class Aurora A covalent inhibitor for the treatment of triple negative breast cancer;European Journal of Medicinal Chemistry;2023-08

4. An Appraisal on Synthetic and Medicinal Aspects of Fused Pyrimidines as Anti Neoplastic Agents;Anti-Cancer Agents in Medicinal Chemistry;2023-03

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