Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors

Published:2011-06 Issue:6 Volume:46 Page:2408-2414
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Liu Wenfeng,Zhu Lingjian,Guo Wei,Zhuang Chunlin,Zhang Yongqiang,Sheng Chunquan,Cheng Pengfei,Yao Jianzhong,Wang Wenya,Dong Guoqiang,Wang Shengzheng,Miao Zhenyuan,Zhang Wannian

Funder

Key Project of Science and Technology of Shanghai

Major Special Project for the Creation of New Drugs

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference21 articles.

1. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

2. Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

3. Phase I Study of Weekly Intravenous Infusions of CPT-11, a New Derivative of Camptothecin, in the Treatment of Advanced Non-Small-Cell Lung Cancer

4. A Tale of Two Tumor Targets: Topoisomerase I and Tubulin. The Wall and Wani Contribution to Cancer Chemotherapy

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