Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu 5 negative allosteric modulation-Reference-Cited by-同舟云学术

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu 5 negative allosteric modulation

Published:2017-02 Issue: Volume:127 Page:567-576
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Gómez-Santacana Xavier,Dalton James A.R.,Rovira Xavier^ORCID,Pin Jean Philippe,Goudet Cyril,Gorostiza Pau^ORCID,Giraldo Jesús^ORCID,Llebaria Amadeu^ORCID

Funder

RecerCaixa foundation

the Marató de TV3 Foundation

the Catalan government

the Spanish Government

ERANET Neuron LIGHTPAINProject

SynBio MODULIGHTOR

Human Brain Project WAVESCALES

Ramón Areces foundation grants

the Agence Nationale de la Recherche

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

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5. The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine;Montana;J. Pharmacol. Exp. Ther.,2009

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