Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis-Reference-Cited by-同舟云学术

Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis

Published:2017-02 Issue: Volume:127 Page:606-620
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Romero Angel H.^ORCID,Medina Rafael,Alcala Anamaría,García-Marchan Yael,Núñez-Duran Jorge,Leañez Jacques,Mijoba Ali,Ciangherotti Carlos,Serrano-Martín Xenón,López Simón E.

Funder

Decanato de Investigación y Desarrollo

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference112 articles.

1. Leishmaniasis Fact sheet N°375. World Health Organization. (http://www.who.int/mediacenter/factsheets/fs375/en/).

2. Leishmaniasis

3. Living in a phagolysosome; metabolism of Leishmania amastigotes

4. Leishmaniasis– current chemotherapy and recent advances in the search for novel drugs

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