Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity

Author:

Brandão Pedro,Loureiro Joana B.,Carvalho Sylvie,Hamadou Meriem Hadjer,Cravo Sara,Moreira Joana,Pereira Daniela,Palmeira Andreia,Pinto Madalena,Saraiva Lucília,Cidade HonorinaORCID

Funder

FCT – Foundation for Science and Technology

European Regional Development Fund

INNOVMAR - Innovation and Sustainability in the Management and Exploitation of Marine Resources

Regional Operational Programme

FCT

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

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2. Control of apoptosis by p53;Fridman;Oncogene,2003

3. Wild type p53 reactivation: from lab bench to clinic;Selivanova;FEBS Lett.,2014

4. P53 and prognosis: new insights and further complexity;Vousden;Cell,2005

5. Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities;Hong;Curr. Drug Targets,2014

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