Investigating isoindoline, tetrahydroisoquinoline, and tetrahydrobenzazepine scaffolds for their sigma receptor binding properties

Author:

Linkens Kathryn,Schmidt Hayden R.,Sahn James J.,Kruse Andrew C.,Martin Stephen F.ORCID

Funder

The Robert A. Welch Foundation

donors of the ADR

a program of the BrightFocus Foundation

Dell Medical School's Texas Health Catalyst

National Institutes of Health

Klingenstein-Simons Fellowship program

National Science Foundation Graduate Research Fellowship

US National Institute of Mental Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference55 articles.

1. Sigma Receptors: Chemistry, Cell Biology, and Clinical Implications,2007

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3. Crystal structure of the human σ1 receptor;Schmidt;Nature,2016

4. Sigma-1 receptor chaperones at the ER- mitochondrion interface regulate Ca 2 + signaling and cell survival;Hayashi;Cell,2007

5. Pharmacology and therapeutic potential of sigma(1) receptor ligands;Cobos;Curr. Neuropharmacol.,2008

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