Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy-Reference-Cited by-同舟云学术

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Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy

Published:2018-03 Issue: Volume:148 Page:140-153
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zha Chuantao,Deng Wenjia,Fu Yan,Tang Shuai,Lan Xiaojing,Ye Yan,Su Yi,Jiang Lei,Chen Yi,Huang Ying,Ding Jian,Geng Meiyu,Huang Min,Wan Huixin

Funder

China International Science and Technology Cooperation Program

National Science and Technology Major Project

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference27 articles.

1. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer;Vermeulen;Cell Prolif,2003

2. Molecular mechanisms controlling the cell cycle: fundamental aspects and implications for oncology;Viallard;Canc. Radiother.,2001

3. Cell-cycle therapeutics come of age;Ingham;J. Clin. Oncol.,2017

4. Cyclin-dependent kinase pathways as targets for cancer treatment;Shapiro;J. Clin. Oncol.,2006

5. Flavopiridol: an old drug with new perspectives? Implication for development of new drugs;Cimini;J. Cell. Physiol.,2017

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1. Discovery of Potential Inhibitors of CDK1 by Integrating Pharmacophore-Based Virtual Screening, Molecular Docking, Molecular Dynamics Simulation Studies, and Evaluation of Their Inhibitory Activity;ACS Omega;2024-09-13

2. Design, synthesis, and antitumor activity of benzimidazole derivatives as CDK4/6 inhibitors;Journal of Molecular Structure;2024-08

3. Exploration of Potential Cyclin-dependent Kinases and their Inhibitors to Combat Abnormal Signalling and Cancer;Current Signal Transduction Therapy;2024-07

4. Cyclin-dependent kinase 4 and 6 in cancer: Exploration of CDK4/6 inhibitors as anticancer agents;Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy;2024

5. Recent Progress in CDK4/6 Inhibitors and PROTACs;Molecules;2023-12-13

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