Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy-Reference-Cited by-同舟云学术

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Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy

Published:2017-09 Issue: Volume:138 Page:1135-1146
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Yuan Zigao,Chen Shaopeng,Chen Changjun,Chen Jiwei,Chen Chengken,Dai Qiuzi,Gao Chunmei,Jiang Yuyang

Funder

Shenzhen Municipal Development and Reform Commission (Disciplinary Development Program for Chemical Biology)

Chinese National Natural Science Foundation

Shenzhen Sci & Tech Bureau

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference54 articles.

1. DNA repair and resistance to topoisomerase I inhibitors: mechanisms, biomarkers and therapeutic targets;Alagoz;Curr. Med. Chem.,2012

2. Drugging topoisomerases: lessons and challenges;Pommier;ACS Chem. Biol.,2013

3. Contemporary challenges in the design of topoisomerase II inhibitors for cancer chemotherapy;Bailly;Chem. Rev.,2012

4. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs;Pommier;Chem. Biol.,2010

5. Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks;Lin;J. Biol. Chem.,2009

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1. Design, synthesis and biological evaluation of matrine contains benzimidazole derivatives as dual TOPOI and PARP inhibitors for cancer therapy;European Journal of Medicinal Chemistry;2024-04

2. Overview of the New Bioactive Heterocycles as Targeting Topoisomerase Inhibitors Useful Against Colon Cancer;Anti-Cancer Agents in Medicinal Chemistry;2024-04

3. New Benzimidazole-Triazole Derivatives as Topoisomerase I Inhibitors: Design, Synthesis, Anticancer Screening, and Molecular Modeling Studies;ACS Omega;2024-03-06

4. Understanding Cancer’s Defense against Topoisomerase-Active Drugs: A Comprehensive Review;Cancers;2024-02-06

5. Design, synthesis and antiproliferative evaluation of new acridine-thiosemicarbazone derivatives as topoisomerase IIα inhibitors;Results in Chemistry;2024-01

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