Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design

Published:2004-05 Issue:5 Volume:39 Page:421-431
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Aguirre Gabriela,Cabrera Eliana,Cerecetto Hugo,Di Maio Rossanna,González Mercedes,Seoane Gustavo,Duffaut Adelina,Denicola Ana,Gil María J.,Martínez-Merino Victor

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference57 articles.

1. Pharmacological Approaches to Antitrypanosomal Chemotherapy

2. Aromatic guanyl hydrazones: Synthesis, structural studies and in vitro activity against Trypanosoma cruzi

3. Chemotherapy of Chagas Disease

4. Thirteenfold increase of chromosomal aberrations non-randomly distributed in chagasic children treated with nifurtimox

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