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Synthesis and structure–activity relationships of harmine derivatives as potential antitumor agents

  • Published:2013-02 Issue: Volume:60 Page:135-143
  • ISSN:0223-5234
  • Container-title:European Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:European Journal of Medicinal Chemistry

Author:

Cao Rihui,Fan Wenxi,Guo Liang,Ma Qin,Zhang Guoxian,Li Jianru,Chen Xuemei,Ren Zhenghua,Qiu Liqin

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference19 articles.

1. Toxicity of Pegamum harmala: review and a case report;Mahmoudian;Iran. J. Pharmacol. Ther.,2002

2. Antitumor and neurotoxic effects of novel harmine derivatives and structure-–activity relationship analysis;Chen;Int. J. Cancer,2004

3. Cytotoxicity of harmine and β-carboline analogs;Ishida;Bioorg. Med. Chem. Lett.,1999

4. Synthesis, acute toxicities and antitumor effects of novel 9-substituted β-carboline derivatives;Cao;Bioorg. Med. Chem.,2004

5. Linear and circular dichroism of harmine and harmaline interacting with DNA;Duportail;Int. J. Biol. Macromol.,1981

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