New quinoxaline 1, 4-di-N-oxides: Anticancer and hypoxia-selective therapeutic agents
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference19 articles.
1. Synthesis and anticancer activity evaluation of new 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethyl-quinoxaline 1,4-di-N-oxide derivatives
2. 3-Amino-2-quinoxalinecarbonitrile. New fused quinoxalines with potential cytotoxic activity
3. 3-Amino-1,2,4-benzotriazine 4-Oxide: Characterization of a New Metabolite Arising from Bioreductive Processing of the Antitumor Agent 3-Amino-1,2,4-benzotriazine 1,4-Dioxide (Tirapazamine)
4. Hypoxia-Selective Agents Derived from Quinoxaline 1,4-Di-N-oxides
5. Enzyme-Activated, Hypoxia-Selective DNA Damage by 3-Amino-2-quinoxalinecarbonitrile 1,4-Di-N-oxide
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1. A quinoxaline-based derivative exhibited potent and selective anticancer activity with apoptosis induction in PC-3 cells through Topo II inhibition;Journal of Biomolecular Structure and Dynamics;2024-03-14
2. Orally bioavailable styryl derivative of rohitukine-N-oxide inhibits CDK9/T1 and the growth of pancreatic cancer cells;European Journal of Medicinal Chemistry;2023-10
3. Quinoxaline 1,4-Dioxides: Advances in Chemistry and Chemotherapeutic Drug Development;Pharmaceuticals;2023-08-17
4. Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective;Pharmaceuticals;2023-02-14
5. Reusable nano-catalyzed green protocols for the synthesis of quinoxalines: an overview;RSC Advances;2023
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