Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model

Published:2014-03 Issue: Volume:74 Page:246-257
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Lee Ju-Hyeon,Seo Seon Hee,Lim Eun Jeong,Cho Nam-Chul,Nam Ghilsoo,Kang Soon Bang,Pae Ae Nim,Jeong Nakcheol^ORCID,Keum Gyochang^ORCID

Funder

KIST Institutional Program

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

1. International Union of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels

2. Molecular Physiology of Low-Voltage-Activated T-type Calcium Channels

3. The design and discovery of T-type calcium channel inhibitors for the treatment of central nervous system disorders

4. T-type Ca2+ channels as therapeutic targets in the nervous system

5. T-type Ca2+ channels in absence epilepsy

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