Synthesis and structure–activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: Application of weakly basic sulfoximine group as novel S4 binding element-Reference-Cited by-同舟云学术

Synthesis and structure–activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: Application of weakly basic sulfoximine group as novel S4 binding element

Published:2012-12 Issue: Volume:58 Page:136-152
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Pandya Vrajesh,Jain Mukul,Chakrabarti Ganes,Soni Hitesh,Parmar Bhavesh,Chaugule Balaji,Patel Jigar,Jarag Tushar,Joshi Jignesh,Joshi Nirav,Rath Akshyaya,Unadkat Vishal,Sharma Bhavesh,Ajani Haresh,Kumar Jeevan,Sairam Kalapatapu V.V.M.,Patel Harilal,Patel Pankaj

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference27 articles.

1. Triggers, targets and treatments for thrombosis;Mackman;Nature,2008

2. New-onset atrial fibrillation and acute coronary syndrome;Lau;Expert Rev. Cardiovasc. Ther.,2010

3. Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality;Cohen;Thromb. Haemostasis,2007

4. Arterial thrombus formation in cardiovascular disease;Lippi;Nat. Rev. Cardiol.,2011

5. DX-9065a, an orally active, specific inhibitor of factor Xa, inhibits thrombosis without affecting bleeding time in rats;Hara;Thromb. Haemostasis,1995

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