Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer

Author:

Yao Dahong,Zhou Yuxin,Zhu Lingjuan,Ouyang Liang,Zhang Jin,Jiang Yingnan,Zhao Yuqian,Sun Dejuan,Yang Shilin,Yu Yang,Wang Jinhui

Funder

National Key R&D Program of China

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference26 articles.

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2. Breast cancer targeted therapy: successes and challenges;The;Lancet,2017

3. What is triple-negative breast cancer?;Irvin;Eur. J. Cancer,2008

4. Triple-negative breast cancer: advancements in characterization and treatment approach;Hurvitz;Curr. Opin. Obstet. Gynecol.,2016

5. Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency;Kawazu;PLoS Genet.,2017

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