Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy-Reference-Cited by-同舟云学术

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Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy

Published:2024-11 Issue: Volume:277 Page:116752
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zhuang Zhen,Miao Yu-Ling,Song Shan-Shan,Leng Guang-Tong,Zhang Xiao-Fei,He Qian,Ding Jian,He Jin-Xue,Yang Chun-Hao^ORCID

Funder

National Natural Science Foundation of China

State Key Laboratory of Drug Research, Chinese Academy of Sciences

Publisher

Elsevier BV

Reference42 articles.

1. Inhibiting the deubiquitinating enzymes (DUBs);Ndubaku;J. Med. Chem.,2015

2. USP7: structure, substrate specificity, and inhibition;Pozhidaeva;DNA Repair,2019

3. The emerging nature of ubiquitin-specific protease 7 (USP7): a new target in cancer therapy;Nininahazwe;Drug Discov. Today,2021

4. A dynamic role of HAUSP in the p53-MDM2 pathway;Li;Mol. Cell,2004

5. Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease;Rawat;Curr. Opin. Cell Biol.,2019

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