Bioisosteric replacement of the carboxylic acid group in Hepatitis-C virus NS5B thumb site II inhibitors: Phenylalanine derivatives
Author:
Funder
Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
Publisher
Elsevier BV
Reference32 articles.
1. Insight into the drug resistance mechanisms of GS-9669 caused by mutations of HCV NS5B polymerase via molecular simulation;Han;Comput Struct Biotechnol J,2021
2. The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection;Bartenschlager;Nat Rev Microbiol,2013
3. Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors;Yang;Bioorg Med Chem Lett,2010
4. Searching for anthranilic acid-based thumb pocket 2 HCV NS5B polymerase inhibitors through a combination of molecular docking, 3D-QSAR and virtual screening;Vrontaki;J Enzyme Inhib Med Chem,2016
5. Identification of N,N-Disubstituted Phenylalanines as a Novel Class of Inhibitors of Hepatitis C NS5B Polymerase;Chan;Journal of Medicinal Chemistry,2003
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