Nur77 increases mitophagy and decreases aggregation of α-synuclein by modulating the p-c-Abl/p-PHB2 Y121 in α-synuclein PFF SH-SY5Y cells and mice

Author:

Yin ShiyiORCID,Shen Mengmeng,Zhang Yongjiang,Wu Jiannan,Song Run,Lai Xiaoyi,Tian Zhenzhen,Wang Tingting,Jin Weina,Yan Junqiang

Funder

Henan University of Science and Technology

Publisher

Elsevier BV

Reference36 articles.

1. Mitochondrial dysfunction and mitophagy in Parkinson's disease: from mechanism to therapy;Malpartida;Trends Biochem. Sci.,2021

2. Mitophagy in degenerative joint diseases;Sun;Autophagy,2021

3. Mitophagy in Parkinson's disease: from pathogenesis to treatment target;Dernie;Neurochem. Int.,2020

4. Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress;Gao;Sci. Rep.,2016

5. Celastrol-induced Nur77 interaction with TRAF2 alleviates inflammation by promoting mitochondrial ubiquitination and autophagy;Hu;Mol Cell,2017

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