New azepino[4,3-b]indole derivatives as nanomolar selective inhibitors of human butyrylcholinesterase showing protective effects against NMDA-induced neurotoxicity-Reference-Cited by-同舟云学术

New azepino[4,3-b]indole derivatives as nanomolar selective inhibitors of human butyrylcholinesterase showing protective effects against NMDA-induced neurotoxicity

Published:2017-01 Issue: Volume:125 Page:288-298
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

de Candia Modesto^ORCID,Zaetta Giorgia,Denora Nunzio,Tricarico Domenico,Majellaro Maria^ORCID,Cellamare Saverio,Altomare Cosimo D.^ORCID

Funder

MIUR

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference48 articles.

1. A review on Alzheimer's disease pathophysiology and its management: an update;Kumar;Pharmacol. Rep.,2015

2. Pharmacotherapy of Alzheimer's disease: current and future trends;Geldenhuys;Expert Rev. Neurother.,2015

3. Cholinesterase inhibitors stabilize Alzheimer's disease;Giacobini;Ann. N. Y. Acad. Sci.,2006

4. Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease;Simoni;J. Med. Chem.,2012

5. Multi-target design strategies in the context of Alzheimer's disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces;Rosini;Neurochem. Res.,2014

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