Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells-Reference-Cited by-同舟云学术

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells

Published:2019-02 Issue: Volume:163 Page:722-735
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Stazi Giulia,Battistelli Cecilia,Piano Valentina^ORCID,Mazzone Roberta,Marrocco Biagina,Marchese Sara,Louie Sharon M.,Zwergel Clemens^ORCID,Antonini Lorenzo,Patsilinakos Alexandros,Ragno Rino^ORCID,Viviano Monica,Sbardella Gianluca^ORCID,Ciogli Alessia,Fabrizi Giancarlo,Cirilli Roberto,Strippoli Raffaele,Marchetti Alessandra,Tripodi Marco,Nomura Daniel K.,Mattevi Andrea,Mai Antonello^ORCID,Valente Sergio^ORCID

Funder

PRIN

AIRC Fellowship

AIRC

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference17 articles.

1. Alkyl and alk-1-enyl ethers of glycerol in lipids from normal and neoplastic human tissues;Snyder;Cancer Res.,1969

2. Tumorigenicity of cell lines with altered lipid composition;Roos;Proc. Natl. Acad. Sci. U. S. A.,1984

3. Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity;Benjamin;Proc. Natl. Acad. Sci. U. S. A.,2013