Discovery of a highly selective FLT3 inhibitor with specific proliferation inhibition against AML cells harboring FLT3-ITD mutation-Reference-Cited by-同舟云学术

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Discovery of a highly selective FLT3 inhibitor with specific proliferation inhibition against AML cells harboring FLT3-ITD mutation

Published:2019-02 Issue: Volume:163 Page:195-206
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Heng Hao,Zhi Yanle,Yuan Haoliang,Wang Zhijie,Li Hongmei,Wang Shuxian,Tian Jieyi,Liu Haichun,Chen Yadong,Lu Tao,Ran Ting,Lu Shuai^ORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Fundamental Research Funds for the Central Universities

China Pharmaceutical University

QingLan Project from Jiangsu Province

National Found for Fostering Talents of Basic Science

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference52 articles.

1. Cytogenetics in acute leukemia;Mrózeka;Blood Rev.,2004

2. Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications;Marcucci;J. Clin. Oncol.,2011

3. The origin and evolution of mutations in acute myeloid leukemia;Welch;Cell,2012

4. Genetics of myeloid leukemias;Kelly;Annu. Rev. Genom. Hum. Genet.,2002

5. FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML;Pratz;Blood,2010

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