Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay-Reference-Cited by-同舟云学术

Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay

Published:2019-10 Issue: Volume:179 Page:837-848
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Mori Shuichi,Iinuma Hiroto,Manaka Noriaki,Ishigami-Yuasa Mari,Murayama Takashi,Nishijima Yoshiaki,Sakurai Akiko,Arai Ryota,Kurebayashi Nagomi,Sakurai Takashi,Kagechika Hiroyuki^ORCID

Funder

Drug Discovery and Life Science Research (Platform for Drug Discovery, Informatics, and Structural Life Science)

Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)

Practical Research Project for Rare/Intractable Diseases

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Sciences KAKENHI

Intramural Research Grant

National Center of Neurology and Psychiatry and the Vehicle Racing Commemorative Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

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4. Ryanodine receptors: structure, expression, molecular details, and function in calcium release;Lanner;Cold. Spring. Harb. Perspect. Biol.,2010

5. Mutations in RYR1 in malignant hyperthermia and central core disease;Robinson;Hum. Mutat.,2006

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