Discovery and structure-activity relationship of novel diphenylthiazole derivatives as BTK inhibitor with potent activity against B cell lymphoma cell lines

Author:

Guo XiaofengORCID,Yang Dongyan,Fan Zhijin,Zhang Nailou,Zhao Bin,Huang Chun,Wang Fangjie,Ma Rongji,Meng Meng,Deng YoucaiORCID

Funder

National Natural Science Foundation of China

Tianjin Natural Science Foundation

International Science & Technology Cooperation Program of China

Fundamental Research Funds for the Central Universities

Nankai University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

1. The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases;Vetrie;Nature,1993

2. Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia;Tsukada;Cell,1993

3. Agammaglobulinemia;Bruton;Pediatrics,1952

4. Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells;Smith;J. Immunol.,1994

5. B cell antigen receptor signaling: roles in cell development and disease;Gauld;Science,2002

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