Synthesis and biological evaluation of pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives as sGC stimulators for the treatment of pulmonary hypertension-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives as sGC stimulators for the treatment of pulmonary hypertension

Published:2019-07 Issue: Volume:173 Page:107-116
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Li Liang^ORCID,Zhang Wenpeng,Lin Feng,Lu Xinqiang,Chen Wei,Li Xingzhou,Zhou Xinbo,Su Ruibin,Wang Lili,Zheng Zhibing,Li Song

Funder

Major New Drugs Innovation and Development

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference35 articles.

1. Discovery of Riociguat (BAY 63-2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension

2. Cardiovascular Effects of Modulators of Soluble Guanylyl Cyclase Activity

3. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

4. Pulmonary Arterial Hypertension

5. Primary pulmonary hypertension

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