Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors

Published:2018-01 Issue: Volume:143 Page:200-215
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Khadka Daulat Bikram,Park Seojeong,Jin Yifeng,Han Jinhe,Kwon Youngjoo,Cho Won-Jea

Funder

Chonnam National University – South Korea

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference44 articles.

1. Proliferation, cell cycle and apoptosis in cancer

2. Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity

3. Exon Array Analyses across the NCI-60 Reveal Potential Regulation of TOP1 by Transcription Pausing at Guanosine Quartets in the First Intron

4. mRNA expression of topoisomerase II in human tumors and normal tissues

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of FTY720 and COH29 as novel topoisomerase I catalytic inhibitors by experimental and computational studies;Bioorganic Chemistry;2024-06

2. Design and synthesis of luotonin A-derived topoisomerase targeting scaffold with potent antitumor effect and low genotoxicity;Bioorganic Chemistry;2024-02

3. Design, synthesis, and biological evaluation of harmine derivatives as topoisomerase I inhibitors for cancer treatment;European Journal of Medicinal Chemistry;2024-02

4. Identification of N-(3-(methyl(3-(orotic amido)propyl)amino)propyl) oleanolamide as a novel topoisomerase I catalytic inhibitor by rational design, molecular dynamics simulation, and biological evaluation;Bioorganic Chemistry;2023-10

5. Electro-organic synthesis of C-5 sulfenylated amino uracils: Optimization and exploring topoisomerase-I based anti-cancer profile;Bioorganic Chemistry;2023-09

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