A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

Author:

Naret Timothée,Bignon Jérôme,Bernadat Guillaume,Benchekroun Mohamed,Levaique Helene,Lenoir Christine,Dubois Joelle,Pruvost Alain,Saller François,Borgel Delphine,Manoury Boris,Leblais Veronique,Darrigrand Romain,Apcher Sébastien,Brion Jean-Daniel,Schmitt Etienne,Leroux Frédéric R.,Alami Mouad,Hamze AbdallahORCID

Funder

CNRS, Univ. Paris-Sud

La Ligue Nationale Contre le Cancer

ANR

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference66 articles.

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4. Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001–2011);Wang;Chem. Rev.,2014

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