Synthesis, biological evaluation and molecular modeling study of thiadiazolo[3,2- a ][1,3]diazepine analogues of HIE-124 as a new class of short acting hypnotics

Author:

El-Subbagh Hussein I.ORCID,Hassan Ghada S.,El-Taher Kamal E.H.,El-Messery Shahenda M.,Al-Azab Adel S.,Abdelaziz Alaa A.-M.,Hefnawy Mohamed M.

Funder

King Saud University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference50 articles.

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3. Chronic abuse of zolpidem;Gericke;J. Am. Med. Assoc.,1994

4. Zaleplon, a novel nonbenzo-diazepine hypnotic, effectively treats insomnia in elderly patients without causing rebound effects. Prime Care Companion J;Ancoli-Israel;Clin. Psychiatry,1999

5. Zaleplon and triazolam physical dependence assessed across increasing doses under a once-daily dosing regimen in baboons;Ator;Drug Alcohol Depend.,2000

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