Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia-Reference-Cited by-同舟云学术

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Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia

Published:2014-10 Issue: Volume:85 Page:268-288
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Jagtap Ajit Dhananjay,Chang Pei-Teh,Liu Jia-Rong,Wang Hsiao-Chun,Kondekar Nagendra B.,Shen Li-Jiuan,Tseng Hsiang-Wen,Chen Grace Shiahuy,Chern Ji-Wang

Funder

Industrial Technology Research Institute

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference74 articles.

1. The acute leukemias;Appelbaum,2011

2. The roles of FLT3 in hematopoiesis and leukemia;Gilliland;Blood,2002

3. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis;Thiede;Blood,2002

4. Clinical impact of internal tandem duplications and activating point mutations in FLT3 in acute myeloid leukemia in elderly patients;Andersson;Eur. J. Haematol.,2004

5. Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia;Smith;Nature,2012

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