One-pot synthesis and antiproliferative activity of novel 2,4-diaminopyrimidine derivatives bearing piperidine and piperazine moieties-Reference-Cited by-同舟云学术

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One-pot synthesis and antiproliferative activity of novel 2,4-diaminopyrimidine derivatives bearing piperidine and piperazine moieties

Published:2014-09 Issue: Volume:84 Page:127-134
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Ma Wei-Feng,Yang Hai-Kui,Hu Meng-Jin,Li Qian,Ma Tian-Zhu,Zhou Zhong-Zhen,Liu Rui-Yuan,You Wen-Wei,Zhao Pei-Liang

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference33 articles.

1. Thiamin pyrimidine biosynthesis in candida albicans: a remarkable reaction between histidine and pyridoxal phosphate;Lai;J. Am. Chem. Soc.,2012

2. Heat shock protein 70 inhibitors. 1. 2,5′-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70;Kang;J. Med. Chem.,2014

3. Synthesis of substituted pyrimidines as corticotropin releasing factor (CRF) receptor ligands;Kuppast;Eur. J. Med. Chem.,2014

4. Design, synthesis and molecular modeling of novel N-acylhydrazone derivatives as pyruvate dehydrogenase complex E1 inhibitors;He;Bioorg. Med. Chem.,2014

5. Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino] -7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5);Reddy;J. Med. Chem.,2014

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2. Design, synthesis, and biological evaluation of N-(pyridin-3-yl)pyrimidin-4-amine analogues as novel cyclin-dependent kinase 2 inhibitors for cancer therapy;Bioorganic Chemistry;2024-02

3. Discovery of new 2,4-diaminopyrimidines derivatives as EGFRT790M kinase inhibitors: a structure-based approach with DFT calculation, drug-likeness, ADME-toxicity properties evaluation and MD simulation;Journal of Umm Al-Qura University for Applied Sciences;2024-01-16

4. Green chemistry approach towards Piperazine: anticancer agents;Journal of Molecular Structure;2023-11

5. Versatile Therapeutic Values of N‐Containing Heterocycles Benzimidazole, Piperazine and Piperidine Hybrids;ChemistrySelect;2023-10-02

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