Synthesis and SAR study of novel tricyclic pyrazoles as potent phosphodiesterase 10A inhibitors-Reference-Cited by-同舟云学术

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Synthesis and SAR study of novel tricyclic pyrazoles as potent phosphodiesterase 10A inhibitors

Published:2014-09 Issue: Volume:84 Page:181-193
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Dore Antonio,Asproni Battistina,Scampuddu Alessia,Pinna Gerard Aime,Christoffersen Claus Tornby,Langgård Morten,Kehler Jan

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

1. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signalling;Conti;Annu. Rev. Biochem,2007

2. Cyclic Nucleotide Phosphodiesterases in Health and Disease;Beavo,2006

3. Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A;Soderling;Proc. Natl. Acad. Sci. U.S.A.,1999

4. Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A);Fujishige;J. Biol. Chem.,1999

5. Isolation and characterization of PDE10A, a novel human 3', 5'-cyclic nucleotide phosphodiesterase;Loughney;Gene,1999

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4. Synthesis of 5,6-Dihydropyrazolo[5,1-a]isoquinolines through Tandem Reaction of C,N-Cyclic Azomethine Imines with α,β-Unsaturated Ketones;Molecules;2023-04-25

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