The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing-Reference-Cited by-同舟云学术

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The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing

Published:2013-04 Issue: Volume:62 Page:777-784
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Ochiana Stefan O.,Pandarinath Vidya,Wang Zhouxi,Kapoor Rishika,Ondrechen Mary Jo,Ruben Larry,Pollastri Michael P.

Funder

National Institutes of Health

National Science Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference36 articles.

1. Human African trypanosomiasis (sleeping sickness): epidemiological update;Wkly. Epidemiol. Rec.,2006

2. Nifurtimox plus eflornithine for late-stage sleeping sickness in Uganda: a case series;Checchi;PLoS Negl. Trop. Dis.,2007

3. Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial;Priotto;The Lancet,2009

4. Target repurposing for neglected diseases;Pollastri;Future Med. Chem.,2011

5. Polyamine metabolism: a potential therapeutic target in trypanosomes;Bacchi;Science,1980

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3. Polypharmacology in Old Drug Rediscovery: Drug Repurposing;Polypharmacology;2022

4. Yeast-based high-throughput screens for discovery of kinase inhibitors for neglected diseases;Advances in Protein Chemistry and Structural Biology;2021

5. Chemogenomics and bioinformatics approaches for prioritizing kinases as drug targets for neglected tropical diseases;Advances in Protein Chemistry and Structural Biology;2021

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