The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT7 receptor antagonists-Reference-Cited by-同舟云学术

The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT7 receptor antagonists

Published:2012-10 Issue: Volume:56 Page:348-360
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zajdel Paweł,Kurczab Rafał,Grychowska Katarzyna,Satała Grzegorz,Pawłowski Maciej,Bojarski Andrzej J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference51 articles.

1. Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile;Agai-Csongor;Bioorg. Med. Chem. Lett.,2007

2. Combinatorial chemistry on solid support in the search for central nervous system agents;Zajdel;Comb. Chem. High Throughput Screen.,2009

3. Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder;Bang-Andersen;J. Med. Chem.,2011

4. Reactant- and product-based approaches to the design of combinatorial libraries;Gillet;J. Comput. Aided Mol. Des.,2002

5. The effectiveness of reactant pools for generating structurally-diverse combinatorial libraries;Gillet;J. Chem. Inf. Comput. Sci.,1997

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