Combination of pharmacophore model development and binding mode analyses: Identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it-Reference-Cited by-同舟云学术

Combination of pharmacophore model development and binding mode analyses: Identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it

Published:2011-09 Issue:9 Volume:46 Page:3942-3952
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Sun Hao-Peng,Zhu Jia,Chen Fei-Hong,Zhang Sheng-Lie,Zhang Yuan,You Qi-Dong

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

1. Structure, Regulation and Function of NF-kappaB

2. Transcriptional profiling of IKK2/NF-κB— and p38 MAP kinasedependent gene expression in TNF-α—stimulated primary human endothelial cells

3. The IKK NF-κB system: a treasure trove for drug development

4. The two NF-κB activation pathways and their role in innate and adaptive immunity

5. Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

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