Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors

Published:2021-04 Issue: Volume:215 Page:113281
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Lin Tingting,Li Jiacheng,Liu Liping,Li Yuanqing,Jiang Hualiang,Chen Kaixian,Xu Pan,Luo Cheng,Zhou Bing^ORCID

Funder

National Science and Technology Major Project

K. C. Wong Education Foundation

National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference39 articles.

1. Cdks, cyclins and CKIs: roles beyond cell cycle regulation;Lim;Development,2013

2. Cyclin-dependent kinases;Malumbres;Genome Biol.,2014

3. Cyclin-dependent kinase 2 controls peripheral immune tolerance;Chunder;J. Immunol.,2012

4. Cyclin-dependent kinase 2 protects podocytes from apoptosis;Saurus;Sci. Rep.,2016

5. Cdk2 activation acts upstream of the mitochondrion during glucocorticoid induced thymocyte apoptosis;Granes;Eur. J. Immunol.,2004

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1. Targeting cyclin-dependent kinases: From pocket specificity to drug selectivity;European Journal of Medicinal Chemistry;2024-09

2. Inhibitors and PROTACs of CDK2: challenges and opportunities;Expert Opinion on Drug Discovery;2024-07-12

3. Modern Approaches to the Synthesis of Pyrazoles (A Review);Журнал общей химии;2024-07-02

4. Design, synthesis, and biological evaluation of N-(pyridin-3-yl)pyrimidin-4-amine analogues as novel cyclin-dependent kinase 2 inhibitors for cancer therapy;Bioorganic Chemistry;2024-02

5. Mechanisms of cytotoxic activity of pyrrole-carboxamides against multidrug-resistant tumor cell sublines;Advances in Molecular Oncology;2023-10-09

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