Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy-Reference-Cited by-同舟云学术

Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy

Published:2022-01 Issue: Volume:227 Page:113953
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Kong Bo,Zhu Zhaohong,Li Hongmei,Hong Qianqian,Wang Cong,Ma Yu,Zheng Wan,Jiang Fei,Zhang Zhimin,Ran Ting,Bian Yuanyuan,Yang Na,Lu Tao,Zhu Jiapeng,Tang Weifang,Chen Yadong^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

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3. New Flavone Derivatives Targeting BET Proteins in Cancer: Synthesis, Structure Analysis and Investigation of Bromodomain Inhibitory Activities**;ChemistrySelect;2023-11-02

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5. Selectivity Mechanism of Pyrrolopyridone Analogues Targeting Bromodomain 2 of Bromodomain-Containing Protein 4 from Molecular Dynamics Simulations;ACS Omega;2023-09-06