Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitors-Reference-Cited by-同舟云学术

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Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitors

Published:2022-01 Issue: Volume:227 Page:113925
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Schiesser Stefan^ORCID,Hajek Peter,Pople Huw E.,Käck Helena,Öster Linda,Cox Rhona J.

Funder

AstraZeneca

Erasmus+

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference36 articles.

1. T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20;Coornaert;Nat. Immunol.,2008

2. The proteolytic activity of the paracaspase MALT1 is key in T cell activation;Rebeaud;Nat. Immunol.,2008

3. CARD-BCL-10-MALT1 signalling in protective and pathological immunity;Ruland;Nat. Rev. Immunol.,2019

4. The paracaspase MALT1: biological function and potential for therapeutic inhibition;Jaworski;Cell. Mol. Life Sci.,2016

5. MALT1 phosphorylation controls activation of T lymphocytes and survival of ABC-DLBCL tumor cells;Gehring;Cell Rep.,2019

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 3D-QSAR, molecular docking and molecular dynamics analysis of pyrazole derivatives as MALT1 inhibitors;New Journal of Chemistry;2023

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