Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition-Reference-Cited by-同舟云学术

Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition

Published:2021-07 Issue: Volume:219 Page:113457
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Ghanim Amany M.,Rezq Samar^ORCID,Ibrahim Tarek S.^ORCID,Romero Damian G.,Kothayer Hend^ORCID

Funder

National Institute of General Medical Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference58 articles.

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3. Shooting three inflammatory targets with a single bullet: novel multi-targeting anti-inflammatory glitazones;Elzahhar;Eur. J. Med. Chem.,2019

4. Effects of various cyclooxygenase and lipoxygenase metabolites on Guinea-pig cerebral arteries;Uski;Gen. Pharmacol.,1992

5. Structure-based design, synthesis, molecular docking study and biological evaluation of 1, 2, 4-triazine derivatives acting as COX/15-LOX inhibitors with anti-oxidant activities;Khoshneviszadeh;J. Enzym. Inhib. Med. Chem.,2016

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