A novel small-molecule fatty acid synthase inhibitor with antitumor activity by cell cycle arrest and cell division inhibition

Author:

Qu Hongyan,Shan Kai,Tang Chunlei,Cui Guozhen,Fu Guoling,Qi Yumin,Cui Jing,Li Jiaqi,Wang Rong,Feng Ninghan,Chen Yong Q.

Funder

National Natural Science Foundation of China

Jiangsu Province Department of Science and Technology

Ministry of Education of the People's Republic of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

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4. Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy;Lu;Bioorg. Med. Chem. Lett,2018

5. Chemical genetics in tumor lipogenesis;Braig;Biotechnol. Adv.,2018

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