Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors
Author:
Funder
National Natural Science Foundation of China
China Pharmaceutical University
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference24 articles.
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2. Therapeutic application of apoptosis signal-regulating kinase 1 inhibitors;Fujisawa;Adv Biol Regul,2017
3. The ASK1-MAP kinase cascades in mammalian stress response;Matsukawa;J. Biochem.,2004
4. ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity;Matsuzawa;Nat. Immunol.,2005
5. Calcium/ASK1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium;Samak;Biochem. J.,2015
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