Design of the naphthyl-diarylpyrimidines as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) via structure-based extension into the entrance channel-Reference-Cited by-同舟云学术

Design of the naphthyl-diarylpyrimidines as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) via structure-based extension into the entrance channel

Published:2021-12 Issue: Volume:226 Page:113868
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Jin Xin,Piao Hu-Ri,Pannecouque Christophe^ORCID,De Clercq Erik^ORCID,Zhuang Chunlin^ORCID,Chen Fen-Er

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference39 articles.

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2. Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years;Zhuang;Acta Pharm. Sin. B.,2020

3. Discovery of uracil-bearing DAPYs derivatives as novel HIV-1 NNRTIs via crystallographic overlay-based molecular hybridization;Zhang;Eur. J. Med. Chem.,2017

4. Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors;Jin;Acta Pharm. Sin. B.,2020

5. Molecular hybridization-inspired optimization of diarylbenzopyrimidines as HIV-1 nonnucleoside reverse transcriptase inhibitors with improved activity against K103N and E138K mutants and pharmacokinetic profiles;Han;ACS Infect. Dis.,2020

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3. Advances in the Synthesis of Diarylpyrimidine as Potent Non-nucleoside Reverse Transcriptase Inhibitors: Biological Activities, Molecular Docking Studies and Structure-activity Relationship: A Critical Review;Current Organic Chemistry;2023-04

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