New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships-Reference-Cited by-同舟云学术

New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships

Published:2021-06 Issue: Volume:218 Page:113387
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Papastathopoulos Athanasios,Lougiakis Nikolaos,Kostakis Ioannis K.^ORCID,Marakos Panagiotis,Pouli Nicole,Pratsinis Harris^ORCID,Kletsas Dimitris

Funder

European Commission

European Regional Development Fund

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference27 articles.

1. Combinatorial drug therapy in cancer - new insights;Bhatia;Life Sci.,2020

2. Targeting apoptosis in cancer chemotherapy;Makin;Expert Opin. Ther. Targets,2002

3. Apoptosis-modulating drugs for improved cancer therapy;Ocker;Eur. Surg. Res.,2012

4. Caspases: a molecular switch node in the crosstalk between autophagy and apoptosis;Wu;Int. J. Biol. Sci.,2014

5. The chemical biology of apoptosis: revisited after 17 years;Yang;Eur. J. Med. Chem.,2019

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