Discovery of novel 4-azaaryl-N-phenylpyrimidin-2-amine derivatives as potent and selective FLT3 inhibitors for acute myeloid leukaemia with FLT3 mutations-Reference-Cited by-同舟云学术

Discovery of novel 4-azaaryl-N-phenylpyrimidin-2-amine derivatives as potent and selective FLT3 inhibitors for acute myeloid leukaemia with FLT3 mutations

Published:2021-03 Issue: Volume:213 Page:113215
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Long Yi,Yu Mingfeng^ORCID,Ochnik Aleksandra M.,Karanjia Jasmine D.^ORCID,Basnet Sunita KC.^ORCID,Kebede Alemwork A.,Kou Lianmeng,Wang Shudong^ORCID

Funder

Channel 7 Children's Research Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference43 articles.

1. FLT3 inhibitors: clinical potential in acute myeloid leukemia;Hospital;OncoTargets Ther.,2017

2. The evolving role of FLT3 inhibitors in acute myeloid leukemia: quizartinib and beyond;Wander;Therapeut. Adv. Hematol.,2014

3. FLT3 inhibition: a moving and evolving target in acute myeloid leukaemia;Leung;Leukemia,2013

4. Midostaurin and emerging FLT3 inhibitors for the treatment of adults with newly diagnosed acute myeloid leukemia with the FLT3 mutation;Gallogly;Expert Rev. Precis. Med. Drug Dev.,2017

5. Acute myeloid leukemia;Döhner;N. Engl. J. Med.,2015

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of indole-grafted pyrazolopyrimidine and pyrazolopyridine derivatives as new anti-cancer agents: Synthesis, biological assessments, and molecular modeling insights;Bioorganic Chemistry;2024-12

2. Developments of Fms-like Tyrosine Kinase 3 Inhibitors as Anticancer Agents for AML Treatment;Current Medicinal Chemistry;2024-09

3. Cu-catalyzed, ligand free syntheses of arylaminopyrimidines in aqueous solution and in silico investigation of their druglikeliness properties;Sustainable Chemistry and Pharmacy;2024-02

4. MARK3 kinase: Regulation and physiologic roles;Cellular Signalling;2023-03

5. Targeting Proliferation Signals and the Cell Cycle Machinery in Acute Leukemias: Novel Molecules on the Horizon;Molecules;2023-01-26