Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria

Author:

Alnabulsi Soraya,Santina Elham,Russo Ilaria,Hussein Buthaina,Kadirvel Manikandan,Chadwick Amy,Bichenkova Elena V.,Bryce Richard A.,Nolan Karen,Demonacos Constantinos,Stratford Ian J.,Freeman Sally

Funder

Jordan University of Science and Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference37 articles.

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2. Human NADPH:quinone oxidoreductase 2, gene structure, activity and tissue expression;Jaiswal;J. Biol. Chem.,1994

3. Catalytic properties of NADH:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase;Wu;Arch. Biochem. Biophys.,1997

4. NADPH:quinone oxidoreductase 2, gene structure, activity and tissue specific expression;Jaiswal;J. Biol. Chem.,1994

5. Bioactivation of 5-(aziridin-1yl)-2,4-dinitrobenzamide (CB1954) by human NADH quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy;Knox;Cancer Res.,2000

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