Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1- b ][1,3,4]thiadiazole and imidazo[2,1- b ][1,3]thiazole scaffolds-Reference-Cited by-同舟云学术

Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1- b ][1,3,4]thiadiazole and imidazo[2,1- b ][1,3]thiazole scaffolds

Published:2015-08 Issue: Volume:101 Page:205-217
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Romagnoli Romeo,Baraldi Pier Giovanni,Prencipe Filippo,Balzarini Jan,Liekens Sandra,Estévez Francisco

Funder

KU Leuven

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference49 articles.

1. Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids;Nepali;Eur. J. Med. Chem.,2014

2. Molecular hybridization: a useful tool in the design of new drug prototypes;Viegas-Junior;Curr. Med. Chem.,2007

3. Advances in the development of hybrid anticancer drugs;Fortin;Expert Opin. Drug Discov.,2013

4. Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach;Solomon;Bioorg. Med. Chem.,2010

5. Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma;Liu;Org. Biomol. Chem.,2013

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