Design, synthesis and biological evaluation of novel 4-arylaminopyrimidine derivatives possessing a hydrazone moiety as dual inhibitors of L1196M ALK and ROS1-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of novel 4-arylaminopyrimidine derivatives possessing a hydrazone moiety as dual inhibitors of L1196M ALK and ROS1

Published:2016-11 Issue: Volume:123 Page:80-89
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Wang Yu,Zhang Guogang,Hu Gang,Bu Yanxin,Lei Hongrui,Zuo Daiying,Han Mengting,Zhai Xin^ORCID,Gong Ping

Funder

Liaoning Excellent Talents in University

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference25 articles.

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4. ALK and ROS1 as a joint target for the treatment of lung cancer: a review;de la Bellacasa;Transl. Lung Cancer Res.,2013

5. EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors;Choi;N. Engl. J. Med.,2010

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